Since ultrafiltration is considered as a “stand-alone” process, based on size exclusion, the UF membranes are classified as an independent microbiological barrier, removing bacteria, viruses as well as larger micro-organisms, such as
cryptosporidium and giardia.
Historically ultrafiltration membranes are only sample tested for virus removal, since this is an expensive test and it takes up to a week to yield results. Standard integrity testing has an accuracy of 3000 nanometers, more than a 100 times the accuracy needed to confirm virus removal. Integrity testing of UF membranes in a range of particle size corresponding to 20-25 nanometers, is of crucial importance to verify the level of sufficient virus removal.